) didn't arrive at genome-wide importance right after adjustment. Given that the outcome sizes remain mainly unchanged when adjusted for BMI, the statistical importance of your associations was diluted from the reduction in sample size.
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Consequently, we largely centered on age-adjusted associations and admit that greater sample measurements are required to further check out the interaction among BMI and PCOS-relevant genetic factors.
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Progress and possession of VR Group’s typical procedure and quality administration methods: governance, methodologies, resources and quality administration program.
In colocalization analyses, all posterior probabilities for a shared causal variant were being decreased than 0.eight. Consequently, we didn't locate more than enough evidence that two Affiliation indicators during the genome-huge association Assessment and gene expression are according to a shared causal variant.
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